A palmitoylethanolamide producing Lactobacillus paracasei improves Clostridium difficile Toxin A-induced colitis.

By |2021-05-07T13:11:06+00:00May 7th, 2021|

Authors: Esposito G, Corpetti C, Pesce M, Seguella L, Del Re A, Vincenzi M, Lattanzi R, Lu J, Sanseverino W, Sarnelli G. Institutions: Department of Physiology and Pharmacology, “V. Erspamer”, Sapienza University of Rome, Rome, Italy Nextbiomics S.r.l., Naples, Italy Department of Clinical Medicine and Surgery, Section of Gastroenterology, University Federico II, Naples, Italy Department [...]

Complementary and alternative treatment in functional dyspepsia

By |2021-04-26T09:44:56+00:00November 10th, 2020|

Authors: Giuseppe Chiarioni, Marcella Pesce, Alberto Fantin, Giovanni Sarnelli Institutions:? Division of Gastroenterology of the University of Verona, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy Department of Clinical Medicine and Surgery, ?Federico II? University of Naples, Naples, Italy Division of Gastroenterology, University of Padua, Azienda Ospedaliera di Padova, Padua, Italy Publication: United European Gastroenterology [...]

HIV-1 Tat-induced diarrhea is improved by the PPARalpha agonist, palmitoylethanolamide, by suppressing the activation of enteric glia

By |2020-11-10T16:52:42+00:00November 10th, 2020|

Authors: Giovanni Sarnelli, Luisa Seguella, Marcella Pesce, Jie Lu, Stefano Gigli, Eugenia Bruzzese, Roberta Lattanzi, Alessandra D?Alessandro, Rosario Cuomo, Luca Steardo & Giuseppe Esposito Institutions: Department of Clinical Medicine and Surgery, ?Federico II? University of Naples, 80131, Naples, Italy Department of Physiology and Pharmacology, ?Vittorio Erspamer?, La Sapienza University of Rome, 00185, Rome, Italy Department [...]

Endocannabinoids in the treatment of gastrointestinal inflammation and symptoms

By |2020-11-10T16:43:56+00:00November 10th, 2020|

Authors: Marcella Pesce, Giuseppe Esposito, Giovanni Sarnelli Institutions: Department of Clinical Medicine and Surgery, ?Federico II? University of Naples, Naples, Italy GI Physiology Unit, University College London Hospital, London, UK Department of Physiology and Pharmacology, `Vittorio Erspamer?, La Sapienza University of Rome, Rome, Italy Publication: Current Opinion in Pharmacology Date: December 2018 Full paper:?https://www.sciencedirect.com/science/article/abs/pii/S1471489218300183 Abstract: [...]

Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice

By |2020-11-10T16:35:42+00:00November 10th, 2020|

Authors: F.Guida, F.Turco, M.Iannotta, D.De Gregorio, I.Palumbo, G.Sarnelli, A.Furiano, F.Napolitano, S.Boccella, L.Luongo, M.Mazzitelli, A.Usiello, F.De Filippis, F.A.Iannotti, F.Piscitelli, D.Ercolini, V.de Novellis, V.Di Marzo, R.Cuomo, S.Maione Institutions: Department of Experimental Medicine, Section of Pharmacology L. Donatelli, Universit? degli Studi della Campania ?Luigi Vanvitelli?, Naples, Italy Department of Clinical Medicine and Surgery, Federico II University of Naples, [...]

Leaky gut, dysbiosis, and enteric glia activation: the trilogy behind the intestinal origin of Parkinson?s disease

By |2020-11-10T16:30:37+00:00November 10th, 2020|

Authors: Luisa Seguella, Giovanni Sarnelli, Giuseppe Esposito Institutions: Department of Physiology and Pharmacology ?V. Erspamer?- Sapienza University, Rome, Italy Department of Clinical Medicine and Surgery, University of Naples ?Federico II?, Naples, Italy Publication: Neural Regeneration Research Date: December 2019 Full paper:?https://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=6;spage=1037;epage=1038;aulast=Seguella Abstract: Early diagnosis of Parkinson?s disease (PD): how we can improve the therapeutic approach:?PD [...]

Diet and functional dyspepsia: Clinical correlates and therapeutic perspectives

By |2020-11-10T16:13:34+00:00November 10th, 2020|

Authors: Marcella Pesce, Martina Cargiolli, Sara Cassarano, Barbara Polese, Barbara De Conno, Laura Aurino, Nicola Mancino, and Giovanni Sarnelli Institutions:? Department of Clinical Medicine and Surgery, "Federico II" University of Naples, Naples 80131, Italy. Department of Clinical Medicine and Surgery, "Federico II" University of Naples, Naples 80131, Italy. sarnelli@unina.it. Publication: World Journal of Gastroenterology Date: [...]

Can the enteric nervous system be an alternative entrance door in SARS-CoV2 neuroinvasion?

By |2020-11-10T16:05:35+00:00November 10th, 2020|

Authors: Giuseppe Esposito, Marcella Pesce, Luisa Seguella, Walter Sanseverino, Jie Lud, Giovanni Sarnelli Institutions: Department of Physiology and Pharmacology, Sapienza University of Rome, Italy Department of Clinical Medicine and Surgery, University of Naples ?Federico II?, Naples, Italy Sequentia Biotech SL, Carrer Comte D?Urgell 240 3D, Barcelona, Spain Department of Human Anatomy, College of Basic Medical [...]

The potential of cannabidiol in the COVID?19 pandemic

By |2020-11-10T15:56:38+00:00November 10th, 2020|

Authors: Giuseppe Esposito, Marcella Pesce, Luisa Seguella, Walter Sanseverino, Jie Lu, Chiara Corpetti,? Giovanni Sarnelli Institutions: Department of Physiology and Pharmacology ?V. Erspamer?, Sapienza University of Rome, Rome Italy Department of Clinical Medicine and Surgery, University of Naples ?Federico II?, Naples Italy Sequentia Biotech, Barcelona, Spain Publication: British Journal of Pharmacology Date: July 2020 Full [...]

Impaired Duodenal Palmitoylethanolamide Release Underlies Acid-Induced Mast Cell Activation in Functional Dyspepsia

By |2021-05-07T06:06:55+00:00November 10th, 2020|

Authors: Giovanni Sarnelli, Marcella Pesce, Luisa Seguella, Jie Lu, Eleonora Efficie, Jan Tack, Fatima, Domenica Elisa De Palma, Alessandra D'Alessandro, Giuseppe Esposito Institutions: Department of Clinical Medicine and Surgery, Naples, Italy Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy Department of Human Anatomy, College of Basic Medical Sciences, China Medical University, Shenyang [...]

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